Research areas

The research in our laboratory focuses on the development of synthetic methods and strategies for preparation of structurally non-trivial small molecules for applications in biomedical research. Our lab is part of an interdisciplinary research platform - Center of Biomolecular and Cellular Engineering - within the International Clinical Research Centre of St. Anne´s University Hospital in Brno and Mayo Clinic in Rochester, Minnesota (USA). Research funding is provided through national and international resources: FP7, EU-Structural Funds, Grant Agency of the Czech Republic, Grant Agency for Health Research of the Czech Republic, Alfred Bader (private support) and Masaryk University.

 

Target molecules

Selective kinase inhibitors

Modulators of adenylyl cyclases

Inhibitors of DNA repair pathways

Small-molecules probes of cell differentiation

Fluorescent probes for biological systems